Development of an amine transaminase-lipase cascade for chiral amide synthesis under flow conditions
نویسندگان
چکیده
An amine transaminase and a lipase have been immobilised in separated reactors containing EziG polymer-coated controlled porosity glass carrier materials to transform 1-phenoxypropan-2-one into the corresponding ( R )-acetamide organic solvent.
منابع مشابه
An efficient single-enzymatic cascade for asymmetric synthesis of chiral amines catalyzed by ω-transaminase.
An efficient single-enzymatic cascade approach for the asymmetric synthesis of chiral amines has been developed, which applies the amino donor 3-aminocyclohexa-1,5-dienecarboxylic acid spontaneously tautomerizing to reach reaction completion with excellent ee values.
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چکیده ندارد.
A Regio- and Stereoselective ω-Transaminase/Monoamine Oxidase Cascade for the Synthesis of Chiral 2,5-Disubstituted Pyrrolidines**
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ژورنال
عنوان ژورنال: Green Chemistry
سال: 2023
ISSN: ['1463-9262', '1463-9270']
DOI: https://doi.org/10.1039/d3gc02426a